EGFR and K-ras mutations in cytologic samples from fine-needle aspirates in NSCLC patients.

نویسندگان

  • Paola Ulivi
  • Wainer Zoli
  • Elisa Chiadini
  • Laura Capelli
  • Piero Candoli
  • Daniele Calistri
  • Rosella Silvestrini
  • Maurizio Puccetti
چکیده

1 Bush A, Hedlin G, Carlsen KH, et al. Severe childhood asthma: a common international approach? Lancet 2008; 372: 1019–1021. 2 Hedlin G, Bush A, Lødrup Carlsen K, et al. Problematic severe asthma in children, not one problem but many: a GALEN initiative. Eur Respir J 2010; 36: 196–201. 3 Lang AM, Konradsen J, Carlsen KH, et al. Identifying problematic severe asthma in the individual child – does lung function matter? Acta Paediatr 2010; 99: 404–410. 4 Payne D, Bush A. Phenotype-specific treatment of difficult asthma in children. Paediatr Respir Rev 2004; 5: 116–123. 5 Lødrup Carlsen KC, Hedlin G, Bush A, et al. Assessment of problematic severe asthma in children. Eur Respir J 2011; 37: 432–440. 6 Bracken M, Fleming L, Hall P, et al. The importance of nurse-led home visits in the assessment of children with problematic asthma. Arch Dis Child 2009; 94: 780–784. 7 Bush A, Saglani S. Management of severe asthma in children. Lancet 2010; 376: 814–825. 8 Marinho S, Simpson A, Soderstrom L, et al. Quantification of atopy and the probability of rhinitis in preschool children: a populationbased birth cohort study. Allergy 2007; 62: 1379–1386. 9 Nathan RA, Sorkness CA, Kosinski M, et al. Development of the asthma control test: a survey for assessing asthma control. J Allergy Clin Immunol 2004; 113: 59–65. 10 Barnes PJ, Jonsson B, Klim JB. The costs of asthma. Eur Respir J 1996; 9: 636–642.

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Rapid KRAS, EGFR, BRAF and PIK3CA Mutation Analysis of Fine Needle Aspirates from Non-Small-Cell Lung Cancer Using Allele-Specific qPCR

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Diagnostic value of cytologic examination of gastrointestinal tract tumors in dogs and cats: 83 cases (2001-2004).

OBJECTIVE To determine results of cytologic examination of fine-needle aspirates and impression smears of gastrointestinal tract tumors in dogs and cats. DESIGN Retrospective case series. ANIMALS 38 dogs and 44 cats with histologically confirmed gastrointestinal tract tumors. PROCEDURES Results of cytologic examination of fine-needle aspirates (n = 67) or impression smears (31) were compa...

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Screening for EGFR and KRAS Mutations in Endobronchial Ultrasound Derived Transbronchial Needle Aspirates in Non-Small Cell Lung Cancer Using COLD-PCR

EGFR mutations correlate with improved clinical outcome whereas KRAS mutations are associated with lack of response to tyrosine kinase inhibitors in patients with non-small cell lung cancer (NSCLC). Endobronchial ultrasound (EBUS)-transbronchial needle aspiration (TBNA) is being increasingly used in the management of NSCLC. Co-amplification at lower denaturation temperature (COLD)-polymerase ch...

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The Utilization of Cytologic Fine-Needle Aspirates of Lung Cancer for Molecular Diagnostic Testing

In this era of precision medicine, our understanding and knowledge of the molecular landscape associated with lung cancer pathogenesis continues to evolve. This information is being increasingly exploited to treat advanced stage lung cancer patients with tailored, targeted therapy. During the management of these patients, minimally invasive procedures to obtain samples for tissue diagnoses are ...

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عنوان ژورنال:
  • The European respiratory journal

دوره 40 1  شماره 

صفحات  -

تاریخ انتشار 2012